Structure-Guided Computational Approaches to Unravel Druggable Proteomic Landscape of Mycobacterium leprae
Leprosy, caused by Mycobacterium leprae (M.leprae), is treated with a multidrug regimen comprising Dapsone, Rifampicin, and Clofazimine.These drugs exhibit bacteriostatic, bactericidal and anti-inflammatory properties, respectively, and control the dissemination of infection in the host.However, the current treatment is not cost-effective, does not